The year is 200X, where all technology is linked to a central computer system. Citizens of DenTech City interface with this network using their personal "NetNavis" (Net Navigators) via their Personal Terminals (PETs). Each NetNavi possesses characteristics and traits like its owner, but also includes enhanced technological powers.

This exciting, futuristic anime-adventure series follows the discoveries and exploits of fifth-grader Lan, whose NetNavi and alter ego is the blue-suited, virus-fighting, virtual superhero named MegaMan. Lan and his friends download different Battle Chips to change their personal NetNavis' gadgetry and defense capabilities. Only by working as a team can they thwart the evil Mr. Wily and his chaos-causing Net crime organization, World Three, who are out to take over the Net in order to wreak havoc on the world . . .